Medical effect of Jojoba oil in the treatment of vaginal diseases

ABSTRACT

In accordance with the present invention Jojoba Oil may be used in accordance with the treatment of and preventative measures associated with Gynecology of Obstetrics and general surgery, as well as in the treatment of eye diseases, inflammation of the internal, middle or external ear, rheumatic pain and arthritis, gingivostomatitis, toothache and dermal diseases. Jojoba oil is a natural product and is characterized by being non-irritant and non-allergic to skin and mucous membrane. This oil has lubricant, moisturizing and soothing properties, as well as having anti-bacterial, anti-inflammatory and anti-oxidant properties. It has a very high healing power and improves blood circulation, and also has high penetration into stratum corneum.

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application is a divisional application of U.S. patentapplication Ser. No. 10/189,888 and filed on Aug. 3, 2002, which claimsforeign priority to Egyptian Patent Application No. 750 and filed onJul. 7, 2001.

FIELD OF THE INVENTION

[0002] The present invention relates to various medical effects of theJojoba oil.

BACKGROUND OF THE INVENTION

[0003] Jojoba oil is used in Lubricating motors and added to somecosmetic preparations. However, such previous uses of Jojoba Oil are notrelated to the new uses subjected to this invention.

SUMMARY OF THE INVENTION

[0004] In accordance with the present invention Jojoba Oil may be usedin accordance with the treatment of and preventative measures associatedwith Gynecology of Obstetrics and general surgery, as well as in thetreatment of eye diseases, inflammation of the internal, middle orexternal ear, rheumatic pain and arthritis, gingivostomatitis, toothacheand dermal diseases.

[0005] Moreover, the Jojoba Oil is preferably extruded in accordancewith the present invention.

[0006] Numerous other advantages and features of the invention willbecome readily apparent from the following detailed description of theinvention and the embodiments thereof, from the claims, and from theaccompanying drawings.

DETAILED DESCRIPTION OF THE EMBODIMENTS

[0007] While the invention is susceptible to embodiments in manydifferent forms, there are shown in the drawings and will be describedherein, in detail, the preferred embodiments of the present invention.It should be understood, however, that the present disclosure is to beconsidered an exemplification of the principles of the invention and isnot intended to limit the spirit or scope of the invention and/or claimsof the embodiments illustrated.

[0008] Natural Jojoba oil is extracted from seeds of Jojoba shrub{Simmondsia Chinensis (LINK) Schnieder}. It is made up of straight chainesters of mono-unsaturated long chain fatty acids and fatty alcohols andhas an average total carbon chain length of 42 carbons, so it isclassified chemically as a liquid wax.

[0009] Jojoba oil is composed entirely of esters of high molecularweight, straight chain mono-ethylenic acids and mono-ethylenic alcohols.The unsaturated acids are mixture of eicosanoic (C20) and docosanoic(C22), with small quantities of palmiloleic (C18) and oleic (C16) acids.The unsaturated alcohols are a mixture of eicosanol and docosanol, withsmaller quantities of hexacosanol and alcohols of lower molecularweight.

[0010] Jojoba oil is non-volatile and free from rancidity, and this isattributed in part to presence of tocopherols (natural anti-oxidant) asa minor constituent and mainly to its wax structure (It has only onealcohol group, so it is not subject to oxidation and will never becomerancid). Furthermore, researches showed that Jojoba oil possesses thesix general factors which increase permeation into stratum cornium: —lowviscosity, high unsaturation, low saponification number, short carbonchain length, low lecithin (Jojoba oil has no lecithin), straight chainmolecule and branched esters.

[0011] Jojoba oil helps to avoid the two important causes of prematureaging of the skin: —dryness and lipid perioxidation. It serves as anexcellent non-occlusive moisturizing agent that enhances the flexibilityand suppleness of the skin. At the same time, its exceptional non-tackyspread and lubricity leave a rich velvety after-feel.

[0012] Jojoba oil is characterized by having 50% of its content asinsaponifiables (Triterpene alcohols and Phytosterols) while othervegetable oil contain only 2-3%. Moreover applying insaponifiables toskin increases elastin formation, which in turn increases skin luster,elasticity and integration. Jojoba Oil also provides skin protection asit has anti-allergic properties, disinfectant, and produces cellstimulation, skin regeneration and stops inflammation. The pH of Jojobaoil is balanced and reveals beneficial effects for dry and damaged skin.

[0013] Jojoba oil is also proven to have anti-inflammatory andanti-microbial effects as well. Five of the most common bacteriaincluding staphylococcus aureus and pseudomonas aeruginosa as well asfungus candida albicans are not able to grow in Jojoba oil.

[0014] One novel way to extract the Jojoba Oil from the Jojoba seeds isas follows. First, it has been determined that the Jojoba seeds contain50-55% of its weight oil. The Jojoba oil is extracted in phase one bypressing the Jojoba seeds under pressure reaching gradually from 1 to35-38 Ton/Inch. About 26-28% oil from the seeds weight is obtained formthe first pressing phase, also called phase one oil, which may be usedfor medical application. After separating the phase-one oil from thecrashed seeds, the residual squeezed seeds are pressed again underpressure up to 100 Ton/Inch, which extracts second phase oil, which maybe used in cosmetic and other fields. Also called second phase oil.Independently, the first-phase-oil and second-phase-oil are elutriatedfor certain time. The elutriated oils are then passed through 4-levelfilter and again elutriated for a predetermined time. The oils arerefiltered through 4-level filter and a higher than the first 4-levelfilter, to obtain the final oil for use. The extracted oil in the firstphase is superior to the ordinary oil especially in the medical effect.

[0015] The extracted Jojoba oil is effectively used in the treatment ofthe following:

[0016] Dermal Diseases

[0017] It has been effectively used with salicylic acid in the treatmentof psoriasis, dandruff, acne and fish skin disease. It has beeneffectively used with zinc oxide in the treatment of napkin dermatitis,skin rash, allergic dermatitis and monilial infection. It has beeneffectively used with the treatment of insect bites and the treatment offungal infect in toes. It is effective in protecting skin fromnon-infective allergic materials such as liquid washing soap. It hasbeen effectively used in treatment of mange, treating first degree burnsand sun burns as well as protecting skin from hazards of ultra violaterays during sun-tanning. It is also elective as a first aid for woundsand treating inflammatory wounds and enhancing healing by primaryintention. It is effective in the treatment of bedsores. It has beenused in assisting treatment of alopecia areata and rogenetica. It hasbeen used to eliminate hair lice. It has been effectively used intreatment of Herpes simplex labialis (cold sores). It has also beeneffectively used in healing diabetic wounds especially diabetic foot.

[0018] Treatment of Gingivostomatitis and Toothache:

[0019] The extracted Jojoba oil has been effectively used with lidocainein the treatment of recurrent aphthous ulceration. It has been used intoothpaste to treat gingivitis and improve the circulation of gingiva.It has been effectively used with zinc oxide in temporary filling. Ithas also been effectively used in the treatment of the dry socket as aside effect of chemotherapy and radiotherapy.

[0020] Rheumatic Pain and Arthritis

[0021] The Jojoba Oil is effective in treating and reliving pains ofpolyarthitis, rheumatic pains, arthralgia, and spondylitis. It iseffective in enhancing the effect of physiotherapy and supporting bodyto regain its physical ability in addition to eliminating the stress andcramps.

[0022] Inflammation of the Ear

[0023] It has been effective in treatment of otitis externa and otitismedia.

[0024] Treatment of Eye Diseases:

[0025] It has been effectively used in treatment of thrombosis.

[0026] General Surgery:

[0027] It has been effectively used as suppositories in treatment ofacute and chronic anal fissure and anal fistula, as well as thetreatment of prostatits, Hiemorroids (at 2^(nd) degree) and early stagesof Varicose Vein.

[0028] Gynecolowy of Obstetrics

[0029] It has been effectively used as a Vaginal suppository intreatment of vaginitis, used in reliving the pain accompanied withdysmenorrhoea, and used in the treatment of nipple crakes and improveits healing.

[0030] The Method of Use

[0031] The Jojoba oil is used by being added to other medicines, forachieving better effects of the novel medicine without any side effects.Examples are as following:

[0032] 1—10% of Jojoba oil by weight, and 0.5% of Lidocainehydrochloride by weight are used for treating the inflammation of mucousmembrane of mouth and condition resulted form administration ofantibiotics for long time.

[0033] 2—50% of Jojoba Oil by weight, and 2% salicylic acid by weightare used in ointment form for treating acne, psoriases, dandruff, sebum(abnormal excessive exudatation of sebaceous glands in skin) and fishskin disease (Thick epidermis being tough and continually scalling)

[0034] 3—50% of Jojoba oil by weight with 8% of zinc oxide weight can beused in treating conditions of skin rash and allergic dermatitis.

[0035] 4—As suppository contain, 20% of Jojoba oil by weight can be usedto treat the anal fissure.

[0036] 5—Vaginal suppository containing 20% of Jojoba oil by weight canbe used in treating non-infective vaginitis.

[0037] Jojoba oil is extracted by pressing the crashed seeds graduallyunder pressure form 1 to 35-38 Ton/Inch to obtain first phase oil, thenmeal well be crashed again and pressed under pressure up to 100 Ton/Inchto obtain second phase oil, then each type of oil will go throughdifferent levels of filtration, since the first phase oil is used formedical application for treating many illnesses.

[0038] As mentioned previously, from seeds, Jojoba oil and itsderivatives are extracted including straight chains of mono-ethylenicacids and mono ethylenic alcohols; further more Jojoba oil isnon-volatile, not subject to oxidation and not liable to rancidity inaddition to its high penetrability to skin as a result of its lowviscosity, high unsaturation, low saponification number, short carbonchain length, low lecithin, straight chain molecule and branched esters.

[0039] As motioned previously, the Jojoba oil is used as anti-bacteria,skin protective, anti-allergic, anti-inflammatory, anti-fungal,improving wound healing and blood circulation in the skin.

[0040] As mentioned previously, Jojoba oil as an essential element, isused for treating many dermal diseases.

[0041] As mentioned previously, Jojoba oil is used as an essentialelement, in the treatment of the inflammation of mucus membrane of themouth, temporary filling and dry sockets.

[0042] As mentioned previously, Jojoba oil is used as a main element intreating and reliving pains of polyarthitis, rheumatic pains,arthralgia, and spondylitis.

[0043] As mentioned previously, Jojoba oil is used as a main element,for treating otitis externa and otitis media.

[0044] As mentioned previously, as a main element, Jojoba oil is used intreatment of thrombosis.

[0045] As mentioned previously, as a main element, Jojoba oil is used intreatment of some general surgeries such as anal fissure, anal fistula,prostatits, and Hiemorroids (at 2^(nd) degree).

[0046] As mentioned previously, Jojoba oil is used as a main element intreatment of vaginitis, and nipple crakes in addition to reliving thepain accompanied with dysmenorrhoea.

[0047] As mentioned previously, compound contain 10% of Jojoba oil byweight and 0.5% of lidocaine hydrochloride by weight, is particularlyeffective in treating mouth ulcer and gingivostomatitis and removing theerythena in addition to reducing Edema associated to theseinflammations—this effect returns to the Jojoba oil properties asanti-bacterial and anti-inflammation substance. Also, the Jojoba oilacts as a painkiller for the conditions. Some of the Jojoba oil'sindications are: gingivostomatitis and conditions resulted from usingantibiotics for long time. Moreover, this compound has no side effects.

[0048] As mentioned previously, preparation contains 50% of Jojoba oilby weight and 2% of salicylic acid by weight and is used for treatingacne, psoriasis dandruff sebum (abnormal) excessive exudatation of sebaceous glands in skin and fish skin disease; it could also be used intreatment of fungal infection as tinia (tinea). This preparation alsohas no side effect.

[0049] As mentioned previously, a suppository containing 20% Jojoba oilby weight can be used to treat the anal fissure. It could relieve theintensity of pains and the complications in many patients as well aseliminating pills. Moreover, this suppository has no side effects.

[0050] As mentioned previously, ointments containing 50% of Jojoba oilby weight with 8% of zinc oxide by weight used in treating condition ofrash, napkin dermatitis, skin inflammation, insect bytes, monilyases,and nipple fissure, no side effects have been resulted from thispreparation.

[0051] As mentioned previously, a vaginal suppository containing 20%Jojoba oil by weight is used to eliminate the vaginitis (acute orrecurrent). This suppository has no side effects.

[0052] Form all the above mentioned benefits, it becomes clear thatJojoba oil, in its all forms and cases, all the illnesses treated withit, has not any side-effects on the human body or environment.

[0053] From the foregoing and as mentioned above, it will be observedthat numerous variations and modifications may be effected withoutdeparting from the spirit and scope of the novel concept of theinvention. It is to be understood that no limitation with respect to thespecific methods and apparatus illustrated herein is intended or shouldbe inferred. It is, of course, intended to cover by the appended claimsall such modifications as fall within the scope of the claims.

1. A method of treating vaginal diseases by applying a composition thatincludes Jojoba oil extruded from Jojoba seeds wherein the extraction ofJojoba oil is prepared by: pressing a Jojoba seed under pressure fromapproximately 1 to approximately 38 tons/inch to obtain a first phaseoil, elutriating said first phase oil for a predetermined amount oftime, filtering said elutriated oil with at least a level four filtercreating a filtered oil, re-elutriating said filtered oil for apredetermined amount of time creating a re-elutriated oil, andre-filtering said re-elutriated oil through a at least a level 4 filter.2. The method of claim 1, wherein the vaginal diseases include but arenot limited to acute or recurrent vaginitis, and Dysmenorrhea.
 3. Amethod of treating acute or recurrent vaginitis, and Dysmenorrhea by avaginal suppository comprising at least Jojoba Oil.
 4. The method ofclaim 3 wherein the vaginal suppository includes approximately 20%Jojoba Oil by weight.